Speaking of mosquitoes, most people have probably been bitten by them. There is no way, and also for the sake of their children, female mosquitoes can only suck the blood of other creatures in order to obtain the nutrients needed for egg development. In fact, a little less blood is nothing. After all, the amount of donated blood is enough for many mosquitoes to have a good meal. However, the wound will become very itchy after being bitten. This is because the saliva secreted by the mosquito contains anticoagulants and anesthetics. Not only will it itch, but what's more frightening is that mosquitoes may carry mosquito-borne pathogens. For example, Aedes aegypti can spread pathogens such as yellow fever, Zika virus and dengue fever. Therefore, how to eliminate mosquitoes has always been a pressing problem for many biologists. As soon as they heard about killing mosquitoes, everyone took out mosquito repellent tablets and electric mosquito swatters from under their beds... Wait, that’s not the case! These are just small tricks. The correct way to kill mosquitoes is to kill them at the source, that is, to make the mosquito larvae “stillborn”. We know that many insects like to lay their eggs in water, and mosquitoes are no exception. However, they also have requirements for water quality when laying eggs. They generally choose to lay eggs in fresh water with relatively low salinity. But there were a few stupid mosquitoes who, perhaps because they thought they were still young and didn't want children, laid their eggs in salty water. Not surprisingly, these eggs died in the salty water. Some people may wonder why mosquitoes die when they lay their eggs in salt water? How do they distinguish between fresh water and salt water? The reason why mosquito eggs die in salt water is simple: the salt concentration is too high, which destroys the physiological structure of the eggs. In order to clarify the distinction between fresh water and salt water, researchers from Rockefeller University and the Kavli Institute for Neuroscience conducted an experiment using genetic and imaging methods. Let's go back to before the mosquito lays eggs. First, the mosquito will determine the egg-laying location. At this time, the mosquito will extend its legs into the water to "taste" the water, thereby activating the mosquito's sensory neurons. Aedes mosquitoes use their feet to taste water Through experiments, it was found that there is a gene called ppk301 in specific neurons in the mosquito's legs and mouth. This gene can sense the presence of water and help mosquitoes correctly distinguish the salt concentration in the water. When the mosquito's legs touch the water source, the ppk301 gene activates neurons and produces an "egg-laying permission" signal. Aedes mosquitoes lay eggs after finding fresh water If the water contains high concentrations of salt, the ppk301 gene will also activate neurons to send a signal, but this signal will prevent the "egg-laying signal", that is, telling the mosquito "Don't lay eggs! The water is too salty!" These two signals allow mosquitoes to detect water sources while also preventing them from laying eggs in high-salinity water that would be lethal to their offspring. Through further experiments, the researchers caused the ppk301 gene to mutate and found that mosquitoes with the mutated ppk301 gene would not be able to correctly choose to lay eggs in fresh water even if they were lucky enough to reach the water's edge. The ability to sense water and salt is critical to life because all living things must regulate the balance of body fluids and ions in order for their physiological systems to function properly. Very small terrestrial insects like mosquitoes have a small surface area and volume, which means they are susceptible to desiccation and must seek out water to survive. Researchers said that based on the "gene controlling the egg-laying location" of mosquitoes, they can make a drug that interferes with the ppk301 ion channel, which can reduce the birth rate of mosquitoes from the source and achieve fewer births, fewer births, and fewer births! |
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