Liver fibrosis is a pathological change caused by chronic liver damage caused by multiple pathogenic factors. It is a pathophysiological process characterized by abnormal proliferation of connective tissue in the liver due to excessive deposition of extracellular matrix components in the liver, which affects liver function. It is an inevitable stage in the development of various chronic liver diseases to cirrhosis. Any liver damage is accompanied by liver fibrosis during the process of liver repair and healing. If the damaging factors cannot be removed for a long time, the fibrosis process will continue for a long time and develop into cirrhosis. The medical community believes that: liver fibrosis can be reversed to normal, but cirrhosis cannot. Therefore, eliminating liver damage and protecting the liver are the key to preventing the occurrence of cirrhosis. Many liver diseases can lead to liver fibrosis, such as viral hepatitis, fatty liver, alcoholic liver disease, and liver damage caused by chemical poisons. If it develops to the late stage of cirrhosis, it will be incurable. Cordyceps sinensis can significantly reduce serum alanine aminotransferase and bilirubin levels, reduce serum type III procollagen and mucin, increase serum albumin concentration, regulate the immune level of viral hepatitis, and enhance the body's ability to clear hepatitis viruses. These effects are very beneficial in preventing the occurrence and development of liver fibrosis. Other medical studies have shown that Cordyceps sinensis has the effect of inhibiting the proliferation of liver fibrosis caused by carbon tetrachloride poisoning. At the same time, clinical studies have also found that Cordyceps sinensis can effectively reduce the biochemical indicators of liver cirrhosis; by inhibiting the expression of a tgfβ1 gene, reducing the expression of the pdgf gene directly related to liver fibrosis, inhibiting the activation of hepatic stellate cells, reducing the synthesis of type I and type III collagen, and alleviating liver fibrosis. To sum up, we can draw the conclusion that Cordyceps sinensis has a good anti-liver fibrosis effect. For patients with various liver diseases, if they want to prevent, stop and reverse liver fibrosis, taking Cordyceps sinensis is a very good choice. |
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