Despite the uncertainty created by the global pandemic over the past two years, the outlook for global pharmaceutical spending has become clearer as healthcare systems and policymakers in both advanced and emerging economies face more predictable challenges and opportunities. Healthcare has demonstrated remarkable resilience during COVID-19, but challenges remain—and evidence-based decision-making is more important than ever. The biggest driver of drug spending over the next five years is expected to be global COVID-19 vaccination, which is unprecedented because of the number of people vaccinated and the speed at which it is expected to be achieved, as well as the frequent subsequent booster shots. But even leaving the pandemic aside, global drug spending continues to be driven by innovation, offset by cost reductions for generics and biosimilars. The report quantifies the impact of these dynamics and examines drug spending and use in 2021 and outlooks to 2026 globally as well as for specific therapeutic sub-branches and countries, laying the foundation for a meaningful discussion about the value, cost, and role of medicines in the context of overall healthcare spending over the next five years. Key findings
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