Can the magic medicine that promises “immortality” and “longevity” really extend life?

If someone says: There really is an elixir of life in this world, what would be your first reaction?

What if I tell you that rejuvenation and longevity are possible to some extent? For example, the following person:

By supplementing with this "elixir of life - NMN", he, who is over 50 years old, has recovered to the state of being in his twenties or thirties. Not only that, but several Nobel Prize winners have endorsed it.

On shopping platforms, the price of NMN health supplements is high. Are NMN health supplements that are advertised as "cell-level" and "time capsule" really effective? Today, let's talk about this "magic drug for immortality" -

01

What is NMN?

What exactly is NMN? Let’s learn about it from its effects.

If you want to achieve immortality, you can’t live without two enzymes in your body: Sirtuns (longevity enzyme) and PARP1 (gene repair enzyme). But in many cases, enzymes cannot work independently and need someone to assist them.

The auxiliary site of these two enzymes is NAD+, referred to as "coenzyme". However, as we age, the synthesis efficiency of NAD+ decreases year by year. At this time, we need to supplement NAD+.

NMN is one of the raw materials for supplementing NAD+. Compared with other raw materials (NR, niacin), NMN can be directly converted into NAD+ in one step, which is why it has been particularly popular in the past two years.

02

NMN Supplements

Is it a tax on IQ?

Putting aside the theory, what are the actual effects of NMN?

At present, there are few clinical studies on NMN in humans. A paper published in the Journal of Endocrinology reported that Japanese scientists asked 10 healthy men aged 40 to 60 to take 100, 250 and 500 mg of NMN orally, and collected blood and urine for examination after 5 hours.

The results showed that oral NMN did not have a significant effect on heart rate, blood pressure, blood oxygen, body temperature, etc., nor did it bring significant changes to vision and sleep. The most critical data - NAD+ levels in tissues and plasma - were not measured in this study.

Based on the current research results, we can only say that supplementing NMN in the human body may have anti-aging effects, but the evidence is insufficient.

Because of this, my country has not yet approved the use of NMN as a food ingredient. You can also find that most of the NMN health products sold on major platforms are cross-border imported goods.

On March 15 this year, a cross-border quality assurance platform conducted random inspections on 19 NMN health products to test their NMN content. The results showed that the label values ​​of 4 products did not match the detected content, and 1 product was not detected at all.

How can such uneven product quality justify the high price of NMN health products?

03

NMN

A new trend in skin care?

In addition to health products, NMN has also quietly set off a craze in the skin care field: in the first half of this year alone, 3 NMN raw materials have completed registration with the State Food and Drug Administration.

According to current research, NMN has anti-photoaging, anti-oxidation, anti-inflammatory, and cell activity-enhancing effects on the skin. However, these studies are almost all based on in vitro biochemical and oral/injection test results in mice.

However, as in the food field, more research is still needed on the action pathways and potential safety of NMN on the skin.

Not only that, NMN is water-soluble and is difficult to be absorbed through the skin barrier.

The three registered raw materials mentioned above are mostly used for skin protection, moisturizing, anti-oxidation, anti-wrinkle and other purposes.

As for the above uses, there are a lot of safe, effective and cost-effective raw materials, so there is no need to rush into the NMN trend.

04

Last words

To sum up: whether in the field of health care products or skin care products, NMN is currently immature and requires more research on its efficacy in humans.

As a consumer, you still need to be cautious when purchasing NMN products. After all, a healthy body is the prerequisite for longevity, and it is by no means possible to achieve the so-called "immortality" by simply supplementing a certain substance.

Otherwise... "I, Qin Shi Huang, will send you money" will come true

Editor | Yuanyuan

Design | Damao

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