Save it now! In the case of influenza A outbreak, in addition to oseltamivir, you can also use these drugs!

Save it now! In the case of influenza A outbreak, in addition to oseltamivir, you can also use these drugs!

Influenza is an acute respiratory infection that is highly contagious and spreads quickly. In my country, it is more likely to spread in winter in the north and in summer and winter in the south. Influenza viruses are divided into three types: A, B, and C. Type A is the most prevalent, followed by type B, which rarely causes an epidemic.

Recently, influenza A has been prevalent in many places. How to treat it? Which drugs are effective? These have become topics of concern to everyone. Oseltamivir has even been snapped up and in short supply. In fact, among the drugs for treating influenza A, in addition to oseltamivir, the following drugs are also very effective. You can choose according to your actual situation.

Western medicine

Abidol

Abidol is a hemagglutinin inhibitor. It inhibits the activity of influenza virus hemagglutinin and prevents the virus from entering human cells. In addition, it can also induce interferon production and exert a broad-spectrum antiviral effect.

The "Expert Consensus on the Integrated Traditional Chinese and Western Medicine Prevention and Treatment of Influenza in Children (2021)" points out that children can refer to Russia's recommended regimen for the treatment of influenza with Abidor Hydrochloride, which is consistent with the recommended usage and dosage for influenza treatment in the "Guidelines for the Rational Use of Antiviral Drugs in Viral Infectious Respiratory Diseases in Children".

Table 1 Usage of Abidol

Mabaloxavir

Mabaloxavir is an innovative Cap-dependent endonuclease inhibitor and the first and only single-dose oral anti-influenza A and B drug approved for the treatment of influenza. Its single oral administration can shorten the infectious period and significantly reduce the duration of influenza symptoms, providing patients with a more convenient treatment plan. In my country, Mabaloxavir is suitable for patients aged 12 years and above with simple influenza A and B, including previously healthy patients and patients at high risk of influenza complications.

Table 2 Usage of Mabaloxavir

Zanamivir

The World Health Organization (WHO) and the U.S. Centers for Disease Control and Prevention (CDC) recommend NAI as the first-line treatment for influenza virus. This type of drug mainly competes with sialic acid, the natural substrate of neuraminidase, to selectively inhibit the activity of neuraminidase on the viral envelope, blocking the enzyme active site, thereby blocking the shedding of virus particles from infected host cells, preventing the virus from spreading between host cells, and thus reducing the replication of the virus in the body.

Representative drugs: Oseltamivir, zanamivir, and peramivir .

Table 3 Usage of Zanamivir

Peramivir

Table 4 Usage of Peramivir

Favipiravir Tablets

Favipiravir is an RNA polymerase inhibitor that mainly inhibits the polymerase acidic protein (PA) and polymerase basic protein 1 (PB1) subunits of the influenza virus ribonucleoprotein, thereby inhibiting mRNA synthesis, causing the virus to undergo fatal mutations and exerting an antiviral effect.

Table 5 Usage of Favipiravir Tablets

Chinese patent medicine

Protect the skin → Jade Screen Granules

Cold symptoms:

①Wind-cold cold granules

②Jingfang Granules

Wind-heat symptoms:

① Wind-heat cold capsule

②Lianhua Qingwen Capsules

Alternating cold and heat → Xiao Chaihu Granules

External cold and internal heat → Fangfeng Tongsheng Pills

Cold cough → Tongxuan Lifei Pills

Wind-heat cough → Lianhua Qingke tablets

Chinese medicine prescriptions for prevention and treatment

Flu prevention prescription:

Honeysuckle 9 g, Forsythia suspensa 9 g, Bamboo leaves 5 g, Schizonepeta tenuifolia 6 g, Burdock seeds 9 g, Licorice root 6 g, Astragalus 12 g, Saposhnikovia divaricata 3 g, Atractylodes macrocephala 15 g.

Influenza treatment prescription for adults (age ≥18 years):

Honeysuckle 20 g, Forsythia suspensa 15 g, Cyperus rotundus 15 g, Isatis root 20 g, Polygonum cuspidatum 20 g, Schizonepeta tenuifolia 10 g, Saposhnikovia divaricata 10 g, Perilla leaf 10 g, Atractylodes lancea 15 g, Burdock fruit 10 g, Platycodon grandiflorum 10 g, and Licorice root 6 g.

Prescription for influenza treatment for children (1 year old ≤ age < 18 years old):

Mulberry leaves 9 g, chrysanthemum 9 g, honeysuckle 9 g, forsythia suspensa 9 g, isatis indigo leaf 9 g, loblolly leaf 9 g, reed root 9 g, coix seed 9 g, licorice 3 g.

Method of taking Chinese medicine

First soak the Chinese medicine in cold water for 20 minutes. The amount of water added should generally exceed the surface of the medicine by 2 to 3 cm. Decoction for 20 minutes at a time and decoct one dose of medicine twice.

Adults: 250 ml each time, 3 times a day.

Children aged 1 to 3 years old: 50 ml each time, 3 times a day. Children aged 4 to 7 years old: 100 ml each time, 2 times a day. Children aged 8 to 13 years old: 100 ml each time, 3 times a day. Children aged 14 years and above: 200 ml each time, 3 times a day.

Other prevention methods

1. Tuina massage

Massage the Hegu point for 3 to 5 minutes each time, and repeat 3 to 5 times. This can regulate the Qi and improve the body's immunity.

2. Moxibustion

Moxibustion on Zusanli, Dazhui, or Shenque point through ginger for 15 to 30 minutes each time, once a day for 3 to 7 consecutive days, can play a preventive role.

3. Anti-plague sachets

Use 3 g of Qianghuo, 3 g of Bupleurum, 3 g of Rhubarb, 3 g of Atractylodes, 3 g of Asarum, and 3 g of Evodia. Grind them into fine powder, put them into a cloth bag, and wear it on your chest.

4. Have a regular routine

Adapt to the changes in nature, maintain a regular schedule, and exercise appropriately.

Special reminder:

Preventive and therapeutic medications must be used under the guidance of a physician.

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