Can “one injection to lose weight” really help you lose weight while lying down?

Losing weight is like going through a trial, which makes people miserable. For the sake of "beauty", fairies have different reasons to lose weight 12 months a year. Recently, there is a hot fat friend circle called "One Needle Slim", which makes fat friends become "Lin Daiyu" in one shot, and the hospital has a phenomenon of "one drug is hard to find". Now let us unveil the mystery of "One Needle Slim". The net name "One Needle Slim" is semaglutide. It is a hypoglycemic drug used to treat type 2 diabetes. Due to its weight loss effect, it is approved for chronic weight management in the United States.

Image source: Pixabay

Why can semaglutide be used for weight loss?

It mainly slows down gastric emptying, allowing food to stay in the stomach for a while longer, increasing satiety and thus suppressing appetite. To put it more bluntly, it is using the side effects of drugs to lose weight.

How effective is semaglutide for weight loss?

A study published in the New England Journal of Medicine recruited 1,961 adults with a BMI ≥ 30 and no diabetes, and gave them semaglutide and placebo, plus lifestyle intervention. After 68 weeks, the subjects in the semaglutide group lost an average of 14.9% of their body weight (2.4% in the placebo group). With such excellent results, in June 2021, the US FDA approved the drug for weight loss.

Can it be used by everyone who wants to control their weight?

No. Even if the drug is internationally approved for weight loss, there are still three restrictions on its use: first, 2.4 mg once a week, for people with BMI ≥ 27 and at least one obesity complication (such as hypertension, type 2 diabetes or high cholesterol); second, for simple obese patients with BMI ≥ 30; third, lifestyle intervention is also required during medication (such as controlling your diet and moving your legs).

Can semaglutide be used for weight loss in the country?

On November 17, Novo Nordisk China held a media conference in Shanghai to announce that the weight loss version of semaglutide (Novowin) was officially launched in China.

Although the weight-loss version of semaglutide (Novozyme) is an important breakthrough in the field of weight-loss therapy, especially providing an effective solution for patients who have not responded to lifestyle interventions, it is not a "miracle drug" and should not be over-reliant on or abused.

Medicine is poisonous

The main adverse reactions of semaglutide are gastrointestinal reactions such as nausea, diarrhea, and vomiting. However, the US FDA black box warning reminds that patients with a personal or family history of thyroid cancer and multiple endocrine neoplasia syndrome type 2 are prohibited from using this drug.

Therefore, weight loss is not the goal, health is the first priority. It is not reliable to try to lose weight by injection just for the sake of beauty and convenience. The only way to get through this is to control your diet and move your legs!

How to lose weight correctly and efficiently?

It's very simple, just one sentence "Burn my calories".

Losing weight requires determination, but it is only one thing in our life. I want to share a passage with you: "Nothing is difficult in the world, only perseverance is the key to success." As long as you apply the key to everything in our life, success is just around the corner!

Source: Chongqing Banan District Second People's Hospital

Author: Dai Xiankun, Department of Pharmacy

Review expert: Bao Zhonghui, deputy chief physician

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